Felix Klein Colloquium: Modeling of carotid artery hemodynamics towards the stroke risk assessment

In medicine, the risk assessment of strokes caused by pathological irregularities in the bifurcation of the carotid artery plays a major role in the patient's optimal treatment decision. 

This decision-making process can be greatly enhanced by detailed flow field data obtained from simulations using patient-specific arterial morphologies. We present our numerical modeling approach to create a CFD database that can guide stroke risk assessment, including hemodynamic shear risk metrics. We investigate the multi-directional behavior of wall shear stress (WSS) based on specially constructed longitudinal tangent vectors using a center-line projection approach and present the utility of longitudinal WSS evaluation for detecting opposing or transverse WSS in slow patient-specific flow. In our fluid-structure interaction model, we generalize the assumption of linear elasticity by a strain-dependent elastic modulus that is consistent with laboratory measurements of compliance and distensibility.

Multiple patient-specific haemodynamic datasets generated by our automated CFD workflow pipeline is used for visual atlases and comparative analysis.

Speaker: Prof. Dr. Anna Hundertmark, RPTU (Campus Landau)

Time: 17:15 - 18:30 o'clock

Place: Building 48, room 210

The lectures of the Felix Klein Colloquium will be held at 17:15 in room 210 of the Mathematics Building 48. Beforehand - from 16:45 - there will be an opportunity to meet the speaker at the colloquium tea in room 580.